The Travelling Salesman Problem (TSP) is one of the most popularCombinatorial Optimization Problem. It is well solicited for the large variety ofapplications that it can solve, but also for its difficulty to find optimal solutions. Oneof the variants of the TSP is the Generalized TSP (GTSP), where the TSP isconsidered as a special case which makes the GTSP harder to solve. We propose inthis paper a new memetic algorithm based on the well-known Breakout Local Search(BLS) metaheuristic to provide good solutions for GTSP instances. Our approach iscompetitive compared to other recent memetic algorithms proposed for the GTSPand gives at the same time some improvements to BLS to reduce its runtime.Keywords: Generalized Travelling Salesman Problem, Breakout Local Search,Memetic Algorithms, Iterated Local Search

In this paper, we propose the first heuristic approach for the vertex separator problem (VSP), based on Breakout Local Search (BLS). BLS is a recent meta-heuristic that follows the general framework of the popular Iterated Local Search (ILS) with a particular focus  on the perturbation strategy. Based on some relevant information on search history, it tries to introduce the most suitable degree of diversification by determining adaptively the number and type of moves for the next perturbation phase. The proposed heuristic is highly competitive with the exact state-of-art approaches from the literature on the current VSP benchmark. Moreover, we present for the first time computational results for a set of large graphs with up to 3000 vertices, which constitutes a new challenging benchmark for VSP approaches.